OpenEvidence revenue and valuation

Specter estimates OpenEvidence's annual revenue at $240M to $390M and its valuation at $12.5B to $18B. The company last reported $150M revenue in December 2025 and was priced at $15B in September 2026.

Updated
Estimated revenue
$240M–$390M
Estimated valuation
$12.5B–$18B
Reported revenue
$150M
Total funding
$1.03B
Founded
2021
Headquarters
Miami, United States
Employees
146

OpenEvidence revenue

OpenEvidence last reported $150M revenue in December 2025. Specter's model puts current revenue between $240M and $390M, anchored to two reported figures.

Line chart of Specter's estimate of OpenEvidence's revenue by month from June 2024 to October 2026, rising from $2.2M to $300M, with a shaded range that puts it at $240M to $390M today. 2 reported figures are marked, from $50M in October 2025 to $150M in December 2025.
Est. revenueConfidence intervalReported figure
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Monthly data
OpenEvidence estimated revenue by month
MonthSpecter estimateLowHighReported figure
$300M$240M$390M
$300M$240M$380M
$290M$240M$350M
$300M$250M$360M
$270M$210M$350M
$250M$193M$310M
$220M$177M$280M
$200M$160M$250M
$183M$147M$230M
$166M$135M$200M
$150M$125M$180M$150M
$87M$71M$106M
$50M$42M$60M$50M
$24M$17M$31M
$20M$13M$27M
$17M$12M$23M
$12M$7.2M$16M
$13M$7.4M$19M
$11M$7.3M$14M
$11M$7M$14M
$11M$6.7M$14M
$6.6M$3.3M$9.9M
$4.7M$3.1M$6.3M
$5.1M$3.7M$6.5M
$4.3M$2.5M$6.1M
$2.8M$1.9M$3.7M
$3.7M$1.4M$6.1M
$2.2M$1.1M$3.4M
$2.2M$1M$3.3M
OpenEvidence reported figures
DateReported figureSource
$150M revenueOpenEvidence raising $250M at $12B.
$50M ARRMedical search engine startup OpenEvidence closes $200M investment led by GV

OpenEvidence valuation

OpenEvidence's valuation rose from $425M at its Seed in July 2022 to $15B at its Series E in September 2026. Specter's live estimate sits between $12.5B and $18B.

Line chart of Specter's estimate of OpenEvidence's valuation by month from June 2024 to October 2026, rising from $800M to $15B, with a shaded range that puts it at $12.5B to $18B today. 6 priced funding rounds are marked, the latest a Series E at $15B in September 2026.
Est. valuationConfidence intervalFunding roundUndisclosed roundNews
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Monthly data
OpenEvidence estimated valuation by month
MonthSpecter estimateLowHighReported valuation
$15B$12.5B$18B$15B (press)
$15B$12.5B$18B$15B (round)
$14.4B$10.6B$19.8B
$13.9B$10.3B$18.9B
$13.4B$10.2B$17.7B
$12.9B$10.1B$16.6B
$12.4B$10B$15.4B
$12B$9.98B$14.4B$12B (press)
$12B$9.83B$14.6B
$12B$9.98B$14.4B$12B (round)
$12B$9.98B$14.4B$12B (press)
$3B$2.5B$3.61B$3B (press)
$6B$4.99B$7.21B$6B (round)
$3.5B$2.91B$4.21B$3.5B (press)
$3.5B$2.91B$4.21B$3.5B (press)
$3.5B$2.91B$4.21B$3.5B (round)
$2.72B$1.99B$3.73B
$2.12B$1.6B$2.82B
$1.65B$1.29B$2.11B
$1.28B$1.04B$1.59B
$1B$830M$1.2B$1B (round)
$970M$450M$2.1B
$950M$490M$1.83B
$920M$460M$1.85B
$900M$480M$1.67B
$870M$460M$1.65B
$850M$470M$1.54B
$820M$520M$1.3B
$800M$510M$1.27B

OpenEvidence funding rounds

OpenEvidence funding rounds
DateRoundRaisedPost-money valuationLead investors
Series E$250M$15BByers Capital, Andreessen Horowitz
SecondaryUndisclosedUndisclosedUndisclosed
Series D$250M$12BDST Global, Thrive Capital
Series C$200M$6BGoogle Ventures
Secondary$15.6MUndisclosedUndisclosed
Series B$210M$3.5BKleiner Perkins, Google Ventures
Series A$75M$1BSequoia Capital
Seed$27M$425MUndisclosed
Seed$5MUndisclosedDaniel Nadler

OpenEvidence competitors

The medical intelligence market is shifting from static repositories to conversational AI synthesis.

OpenEvidence and its competitors by estimated revenue and valuation
CompanyRevenueValuation
OpenEvidence$240M–$390M$12.5B–$18B
UpToDate$47M–$230MNo estimate
ClinicalKey Now$600K–$1.3M$2.2B–$13B
PulseLife$3.1M–$9.4M$4.6M–$28M
Vera Health$3.9M–$15M$195M–$230M

OpenEvidence revenue and valuation FAQ

What is OpenEvidence's revenue?

Specter estimates OpenEvidence's annual revenue at $240M to $390M as of October 2026. OpenEvidence last reported $150M revenue in December 2025.

What is OpenEvidence's valuation?

OpenEvidence's latest post-money valuation is $15B, from a September 2026 Series E. Specter's live estimate is $12.5B to $18B.

What is OpenEvidence's revenue multiple?

OpenEvidence is valued at about 100× revenue, based on its $15B September 2026 valuation and $150M last reported revenue. That works out to roughly $1.03M of revenue per employee.

How much funding has OpenEvidence raised?

$1.03B across nine rounds, from a $5M Seed in November 2021 to a $250M Series E in September 2026.

Who invested in OpenEvidence?

31 investors, including Andreessen Horowitz, Byers Capital, DST Global, Google Ventures, Kleiner Perkins and Thrive Capital.

Who are OpenEvidence's competitors?

UpToDate, ClinicalKey Now, PulseLife and Vera Health. Specter ranks 29 competitors for OpenEvidence.

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